Steering Your Path to the Clinic, Complimentary Breakfast Workshop, June 29, Oxford UK
07/06/2023
How confident are you in your route to the clinic? There are multiple hurdles to be navigated, many of which can knock your development programme off course and threaten that all-important milestone. Optimising your clinical study design, so that it delivers the endpoints you need, without wasting time and budget, is crucial to keeping your […]
First Dose Administered in Phase I Trial of Novel Treatment for Cognitive Impairment Associated with Schizophrenia
09/03/2023
February 27, 2023 Simbec-Orion are pleased to share that dosing with MDI-26478, Cardiff University’s Medicines Discovery Institute’s (MDI) potential novel treatment for cognitive impairment associated with schizophrenia and a range of disorders connected with the brain and central nervous system, has commenced in our MHRA Accredited Phase I Unit in South Wales. This is an […]
Mission Therapeutics Successfully Completes First Clinical Assessment for Lead DUB Program, MTX652
09/01/2023
The successful delivery of another Phase I clinical trial by the team at Simbec-Orion has resulted in the achievement of a significant milestone for Mission Therapeutics. MTX652 was shown to be well tolerated and safe up to a single dose of 200mg and multiple doses of 100mg once daily for 14 days. We share the […]
Sustained clinical response in a patient with metastatic breast cancer treated with MP0274
17/11/2022
Today we celebrate the success of our colleague, and Scientific Advisory Board member, Dr Samson Fung. Dr Fung was recently co-authored in a publication by JCO Precision Oncology released on 4th November, 2022, for his work as a study director in a Ph I FIH clinical study in patients with metastatic breast cancer. Believed to […]
Simbec-Orion supports AL-S Pharma with Phase II ALS Study
21/10/2022
Amyotrophic lateral sclerosis (ALS) is a rare, progressive neurodegenerative disease that affects the motor neurons controlling voluntary muscle movement. The onset is usually quite gradual, with patients noticing muscle weakness – including tripping or dropping things, in the early stages. Not all patients with ALS experience the same symptoms, and progression rate and survival time […]
Simbec-Orion Scientists Shortlisted for Wales STEM 2022 Finals
30/09/2022
We are proud to share that two of our Simbec-Orion colleagues are amongst the Welsh businesses and individuals shortlisted in the Wales STEM Awards 2022, which celebrate those making a difference to, and championing, Science, Technology, Engineering, and Maths (STEM) in Wales. The awards celebrate those leading the sector in Wales, those businesses creating an […]
Wales STEM Award Nominations for Two Simbec-Orion Scientists
30/09/2022
We are thrilled that two of our Simbec-Orion colleagues are amongst the Welsh businesses and individuals shortlisted in the Wales STEM Awards 2022, which celebrate those making a difference to, and championing, Science, Technology, Engineering, and Maths (STEM) in Wales. The awards celebrate those leading the sector in Wales, those businesses creating an impact on […]

