Who We Are

Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare disease clinical trial designs. We are perfectly structured to provide full-service clinical development solutions for small and mid-size drug developers – headed up by a centralised leadership team.

With a focus on tailor-made and scalable solutions, we’ll adapt our delivery style, communications and operations to suit the demands of your project, helping you achieve your clinical and commercial objectives. Because our goal is the same as yours; to improve patients’ lives.

Our company culture is defined by our values: caring ambitiously, tight knit teams, dedicated to delivery, forward thinking, and radically honest.

The Board

Aize Smink

Chief Operating Officer

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Anand Jain

Chairman of the Board

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Ceri Edwards

Managing Director, Clinical Pharmacology

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Fabrice Chartier

Chief Executive Officer

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John Gahan

Chief Financial Officer

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Anita Cooper

Non-Executive Director

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Adam Richardson

Non-Executive Director

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Senior Leadership Team

Jim Kendall

Chief Information Officer

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Melissa Jones

Chief Commercial Officer

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Enrique Rafalin

Senior Director, Group Head of Quality Assurance

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Ana Smith

Chief People Officer

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Aize Smink

Chief Operating Officer

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Ceri Edwards

Managing Director, Clinical Pharmacology

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Fabrice Chartier

Chief Executive Officer

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John Gahan

Chief Financial Officer

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Developing therapies for rare disease
Cost efficient trial design

The clinical development of orphan drugs represents a very interesting challenge that demands thoughtful and innovative designs. Orphan Drug clinical developers must become serious reliable players in the orphan space to attract investors and motivate all the stakeholders

Therapy Areas

in Detail

The clinical research organisation with wide therapeutic experience, specialising in rare disease and oncology clinical development solutions.

Rare Diseases

Oncology

Other Therapeutic Areas

Financial and regulatory
advantages of conducting early phase clinical research studies

Simbec-Orion with the Department for International Trade (DIT) hosted an expert panel discussion to examine the financial and regulatory advantages for the US companies conducting Early Phase research in the UK.

Our clinical
development solutions

We support clients with a range of functional and full-service clinical development solutions. Our wide range of clinical services include clinical trial management, clinical pharmacology, central laboratory support, and more – all customised to your project’s specific needs. Find out more about our clinical development services.

Clinical Pharmacology

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As a full-service facility, we carry out all types of studies at our purpose-built site. 90% of our work is with Investigational Medicinal Products, in all drug delivery routes.

Clinical pharmacology is a key part of our CRO services, so if you need support managing a clinical trial, there are many ways our expertise can help.

Clinical Trial Management Services

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Our expert biometrics team delivers accurate and adaptive clinical data management services that support the success of your drug development programme.

Conducting statistical analysis, planning, and reporting across all clinical phases, they will create a quality biostatistical framework that presents clinical trial data clearly and correctly for regulatory agencies.

Central Laboratory Services

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We are a CRO with in-depth experience in the most challenging therapeutic areas, including oncology, rare and orphan diseases, respiratory, dermatology, vaccines and anti-infectives.

With more than 25 years’ experience in the clinical research sector, we offer a comprehensive service you can trust – with an international reach. All with the highest level of quality, agility, and responsive customer service.

A full-service agile CRO
for complex clinical studies

For the last four decades, we have been providing clinical trial management services across a wide range of therapeutic indications and phases. Our passion is rare diseases and oncology.
Our experience defines our expertise
Responding to the needs of our clients has made us the CRO we are today; a partner, offering full-service clinical development with the size, agility and structure to respond rapidly when needed.
From Phase I clinical pharmacology studies through to Phase III rescue studies and post-marketing, we are here to take on the challenge – whatever the indication or compound you are passionate about, wherever you are in your clinical development journey.

What our
Clients Say About Us

The people working at Simbec Orion are dedicated, very professional and they cover all aspects of clinical research. A team will be set up for your project, who will have a strong focus on your study in a very open minded and friendly atmosphere. The studies I have outsourced to Simbec Orion, have been successfully managed and performed. I will use Simbec Orion in the future and I can strongly recommend them to other pharmaceutical companies.

Tina Lidén Mascher, Head of Clinical Operations

Klaria AB

Got a question?
Get in Touch or Submit an RFI/RFP

Our team is on hand to answer any questions you might have relating to the work we do at Simbec-Orion. Just fill in the form below, making sure to tick the boxes that apply, and we’ll respond as quickly as we can.

Looking to volunteer for a clinical trial?

Visit our dedicated volunteer website here, or email [email protected]

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