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Understanding Oncology Oncology is an area of medicine and clinical research that focuses on the study, treatment, prevention, and management of cancer. Like other therapeutic areas of research, oncology treatments undergo testing in clinical trials. Oncology clinical research has advanced the effectiveness and safety of cancer therapies, providing hope to millions of cancer patients worldwide. Oncology […]

Scientists investigate thousands of new drug ideas each year. Whilst many of these ideas are taken through to clinical stages of development, not all drugs successfully make it to market.  There are 3 main stages of clinical trials: phases 1, 2 and 3. At the end of each phase, investigators and regulatory authorities evaluate whether […]

In this series, we will be speaking with Simbec-Orion staff and asking them about their day-to-day work, what it involves and how they see their role developing in the future. In our first post, we are meeting Dr Maria Kozlak, a Clinical Research Associate (CRA) at Simbec-Orion. We’ll take a look at a day in […]

Cancer research is one of the most commonly investigated areas of clinical study. Oncology research has accelerated the development of advanced chemotherapy drugs, which are now generally less toxic as a result. Conventional chemotherapy drugs once primarily used cytotoxic compounds to target cancerous cells, which would also damage surrounding cells as a result.  Now, with […]

Clinical research is a broad area of patient care that investigates diseases, diagnostic methods and treatments, and plays a crucial role in progressing medical solutions to improve global health. This helps develop medical knowledge of how to identify, prevent, treat and manage health conditions. The importance that clinical research has on the development of medical […]

Translational research takes scientific findings from more basic patient settings and translates these into insights that are used to develop treatment options. In essence, translational research establishes a bridge between basic research and clinical practice.   Translational research has become increasingly popular in biomedical sciences over recent years, particularly in the field of oncology.  This approach […]

During phase 1 clinical trials, it is essential to establish safe and recommended dosages of the study drug or treatment. To determine this, dose escalation methods are used to examine the most tolerable dosage of the drug in patients early on in the trial. Read about the stages of clinical trials. The objective of dose […]