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Amyotrophic lateral sclerosis (ALS) is a progressive neurological condition that affects motor neurons in the brain and spinal cord. These nerve cells control voluntary muscle movement. As ALS progresses, motor neurons deteriorate and die, leading to increasing muscle weakness and loss of physical function. What Is ALS? Motor neurons transmit signals from the brain and […]

World Cancer Day, observed each year on 4th February, is a global initiative focused on raising awareness of cancer and accelerating action across prevention, diagnosis, treatment and research. For organisations working in clinical research and drug development, the day is also an opportunity to reflect on the progress made, and the work still required to […]

Chordoma is a very rare cancer, diagnosed in only around one in a million people each year. It develops slowly, close to critical structures in the spine and skull base, meaning treatment can be complex and the path to diagnosis long. With limited therapeutic options and a high risk of recurrence, continued oncology-led clinical research […]

 A new study by scientists at University College London and Great Ormond Street Hospital has demonstrated promising results in the treatment of T-cell acute Lymphoblastic Leukaemia (T-ALL), a rare and aggressive blood cancer What the study reveals. This groundbreaking research introduces BE-CAR7, a world-first base-edited Chimeric antigen receptor (CAR) T-cell therapy used in humans. The […]

Good Laboratory Practice (GLP) is a set of criteria used to ensure quality assurance in non-clinical studies. GLP principles are concerned with the organisational processes by which studies are planned, performed, monitored, recorded, reported and archived. These guidelines support the integrity, reliability and traceability of safety data used for regulatory submissions.  GLP is commonly applied […]

Alpha-1 Antitrypsin Deficiency (AATD) is a hereditary condition that increases the risk of serious lung and liver disease. It occurs when the body produces too little of a protective protein called Alpha-1 Antitrypsin (AAT). Without adequate AAT, lung tissue becomes more susceptible to inflammation and progressive damage, while abnormal protein can build up in the […]